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A supercentenarian (sometimes hyphenated as super-centenarian) is someone who has lived to or passed their 110th birthday. This age is achieved by about one in 1,000 centenarians.[1] Anderson et al. concluded that supercentenarians live a life typically free of major age-related diseases until shortly before maximum human lifespan is reached (125 years).[2]

IncidenceEdit

There are estimated to be 300–450 living supercentenarians[3] in the world, though approximately 100 verified cases are known.[4]

The first verified supercentenarian in human history died in the late nineteenth century. Until the 1980s, the oldest age attained by supercentenarians was 115, but this has since been surpassed.

MorbidityEdit

Research on the morbidity of supercentenarians has found that they remain free of major age-related diseases (e.g., stroke, cardiovascular disease, dementia, cancer, Parkinson's disease, and diabetes) until the very end of life when they die of exhaustion of organ reserve, which is the ability to return organ function to homeostasis.[5] About 10% of supercentenarians survive until the last 3 months of life without major age-related diseases as compared to only 4% of semisupercentenarians (age range 105–109 years) and 3% of centenarians.[5]

See alsoEdit

ReferencesEdit

  1. Maier, H., Gampe, J., Jeune, B., Robine, J.-M., Vaupel, J. W. (Eds.) (2010). Supercentenarians. Germany: Max Planck Institute for Demographic Research, 325. ISBN 978-3-642-11519-6. 
  2. B. M. Weon; J. H. Je (2009). "Template:Link". Biogerontology 10: 65–71. doi:10.1007/s10522-008-9156-4. 
  3. Validated living supercentenarians
  4. http://supercentenarian-research-foundation.org/TableE.aspx
  5. 5.0 5.1 Anderson, Stacy L.; Sebastiani, Paola; Dworkis, Daniel A.; Feldman, Lori; Perls, Thomas T. (2012). "Template:Link". The Journals of Gerontology: Series A 67A: 395–405. doi:10.1093/gerona/glr223, http://biomedgerontology.oxfordjournals.org/content/67A/4/395.full. Retrieved on Template:Date. 

External linksEdit

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